O. Dale Williams, PhD
Professor
Division of Preventive Medicine
Contact Information:
Medical Towers 619
1717 11th Avenue South
Birmingham, Alabama 35205
Phone: 205-996-2875
Fax: 205-975-5153
odalew@uab.edu
Research Interests
Dr. Williams is the Division's Associate Director and also directs its Data, Information, and Statistics Core (DISC) and its Multi-center Studies Coordinating Center (MSCC). DISC provides research infrastructure support for the Division and includes units for biostatistics, data management, Information systems, and statistical computing support. The MSCC provides coordinating center support for several large studies, including CARDIA, the CARDIA Fitness Study (CFS), and the Dental Practice Based Research Network (PBRN). Dr. Williams serves as the PI for the Coordinating Centers for CAMUS, Dental PBRN, and for the Fogarty International Center funded Clinical Research Training for Studies of CVD in India. He has a long standing interest in large scale collaborative studies and coordinating center operations, research training, cardiovascular disease epidemiology and outcomes research.
Educational Background
University of North Carolina, PhD, 1971
University of North Carolina, MPH, 1965
Southeastern Louisiana University, BS, 1962
Professional Activities
Data and Safety Monitoring Board, Infant Study of Inhaled Saline in Cystic Fibrosis, National Heart, Lung and Blood Institute, 2008-present
Executive Committee, Complementary and Alternative Medicine For Urological Symptoms (CAMUS) Study, National Institute of Diabetes and Digestive and Kidney Diseases National Center for Complementary and Alternative Medicine Office of Dietary Supplements, National Institutes of Health, 2008 - present
Steering Committee, Complementary and Alternative Medicine For Urological Symptoms (CAMUS) Study, National Institute of Diabetes and Digestive and Kidney Diseases National Center for Complementary and Alternative Medicine Office of Dietary Supplements, National Institutes of Health, 2008 - present
National Heart, Lung, and Blood Institute Strategic Plan, Division of Lung Diseases, Theme #5: Enabling Therapeutic Trials and Translational Research Working Group, June 1-2, 2006
Directors Committee, CONDOR, National Institute of Dental and Craniofacial Research, 2005-present
Bioinformatics Committee, CONDOR, National Institute of Dental and Craniofacial Research, 2005-present
Executive Committee, CARDIA Study, 2004-present
Data and Safety Monitoring Board, Effectiveness and Safety of Intermittent Antimicrobial Therapy for the Treatment of New Onset Pseudomonas Aeruginosa Airway Infection in Young Patients with Cystic Fibrosis (EPIC), Division of Lung Diseases National Heart, Lung, and Blood Division, 2004-present
Data and Safety Monitoring Board, RCT of Elidel use in infants with mild to moderate atopic dermatitis, NOVARTIS Pharmaceuticals Corporation, 2004-present
Data and Safety Monitoring Board, Hematopoietic Stem Cell Transplant Trials, Division of Allergy, Immunology, and Transplantation, National Institute of Allergy and Infectious Diseases, 2003-present
Executive Committee, Cardiovascular Disease in Young Adults (CARDIA) Study, National Heart, Lung and Blood Institute, 1992-present
ata and Safety Monitoring Board, Carotid evascularization with Endarterectomy or Stenting Systems (CARESS), International Society of Endovascular Specialists, 2001- 2006
HIV Treatment Regimen Adherence Working Group, American Public Health Association, 1999-2000
Cardiovascular Assessment Expert Panel, Wyeth-Ayerst Research, 1997-2000
Data and Safety Monitoring Board, National Emphysema Treatment Trial (NETT), National Heart, Lung and Blood Institute, 1997-2004
Data and Safety Monitoring Board, Alendronate Long Term Care Study, University of California at San Francisco, 1997-1998
Data and Safety Monitoring Committee, PACT Study, George Washington University, 1995-1997
Mortality and Disability in the New Independent States Workshop, Committee on Population, National Academy of Sciences, Washington, DC, September 8-9, 1994
Adult Health Priorities and Policies in the New Independent States Workshop, National Academy of Sciences, Washington, DC, November 17-18, 1994
Institute of Medicine, (IOM) Roundtable on the Roles of Academic Health Centers in Clinical Research and Education, 1993-94
National Heart, Lung, and Blood Institute Task Force on Research in Epidemiology and Prevention of Cardiovascular Diseases, 1993-94
Steering Committee, Cardiovascular Disease in Young Adults (CARDIA) Study, National Heart, Lung and Blood Institute, 1992-present.
Chair, Data and Safety Monitoring Board for the Heart and Estrogen/Progestin Replacement Study (HERS), Wyeth-Ayerst Research, 1992-1998
Technology Assessment Conference Panel, Methods for Voluntary Weight Loss and Control: NIH Technology Assessment Conference, Bethesda, MD, March 30 - April 1, 1992
Safety and End Points Monitoring Committee for the Carotene and Retinol Efficacy Trial (CARET) Fred Hutchinson Cancer Research Center, funded by the National Cancer Institute, 1990-1996
Data and Safety Monitoring Committee for the Lipoprotein and Coronary Atherosclerosis (LCAS) Study funded by Sandoz Research Institute, 1990-1996.
Biomedical Operations External Advisory Board, Sandoz Research Institute, 1990-1992
Review Panel, Secretary's Award for Innovations in Health Promotion and Disease Prevention, Association of Schools of Public Health, Washington, DC, 1989
Medical Follow-up Agency, Institute of Medicine, National Academy of Sciences, 1989.
Evaluation Panel, National Bone Marrow Registry, National Institutes of Health, Bethesda, MD, January 24-25, 1988
Abstract Committee and Session Co-chair; First National Cholesterol Conference, 1988
Safety and Data Monitoring Board, Early Intervention for Chronic Obstructive Pulmonary Disease (Lung Health Study), National Heart, Lung, and Blood Institute, 1986-1993
Workshop on Diagnosis and Monitoring of Hypercholesterolemia: A National Health Issue, National Institutes of Health, Bethesda, MD, 1986
Steering Committee, Atherosclerosis Risk in Communities Study, National Heart, Lung, and Blood Institute, 1985-91
Monitoring Committee, National Acute Spinal Cord Injury Study II, National Institute of Neurological and Communicative Disorders and Stroke, 1985-1990
NHLBI Workshop on Assessment of Quality of Life in Clinical Trials of Cardiovascular Therapies, June 20 - 21, 1983
Policy Advisory Board, National Survey of Visual Acuity Impairment and Its Causes, National Eye Institute, 1980-84
Clinical Applications and Prevention Advisory Committee, National Heart, Lung, and Blood Institute, 1980-83
Monitoring Committee, National Acute Spinal Cord Injury Study I, National Institute of Neurological and Communicative Disorders and Stroke, 1979-85
Advisory Committee, Coordinating Center of the National Cooperative Dialysis Study, National Institute of Arthritis, Metabolism, and Digestive Diseases, 1979-80
Operations Committee, Cooperative Study on Anti-Epileptic Drugs, Veterans Administration, 1978-84
Resource Committee, Coordinating Center Models Project, National Heart, Lung, and Blood Institute, 1977-79
Chair, Policy Advisory Group, Diabetic Retinopathy Vitrectomy Study, National Eye Institute, 1976-82
Member, Directors Committee, Lipid Research Clinics Program, National Heart, Lung, and Blood Institute, 1975-87
Member, Nutrition Data Collection Joint Executive Board, National Heart, Lung, and Blood Institute, 1974-80
Various site visit teams and review panels for different institutes, National Institutes of Health, 1973-present
Selected Recent Publications
(selection of recent publications out of over 100 total)
Bibbins-Domingo K, Pletcher MJ, Lin F, Vittinghoff E, Gardin JM, Arynchyn A, Lewis CE, Williams OD, Hulley, SB. Heart Failure and Ventricular Dysfunction In Black and White Young Adults: The Coronary Artery Risk Development In Young Adults (CARDIA) Study, New England Journal of Medicine, 2009Mar19, 360 (12):1179-11903
Pisu M, Richman J, Allison JJ, Williams OD, Kiefe CI. Pharmaceuticals Companies’ Medication Assistance programs: Potentially Useful but Too Burdensome to Use? South Med J. 2009 Feb 9.
Westfall JM, Kiefe CI, Weissman NW, Goudie A, Centor RM, Williams OD, Allison JJ. Does interhospital transfer improve outcome of acute myocardial infarction? A propensity score analysis from the Cardiovascular Cooperative Project. BMC Cardiovascular Disorders; 2008 Sep 9, 8:22.
Reiner A, Wurfel MM, Lange LA, Carlson CS, Nord AS, Carty CL, Rieder MJ, Desmarais C, Jenny NS, Iribarren C, Walston JD, Williams OD, Nickerson DA. Polymorphisms of the IL1-receptor antagonist gene (IL1RN) are associated with multiple markers of systemic inflammation. Arteriosclerosis, Thrombosis, and Vascular Biology. 2008 May 1 (epublished ahead of print).
Enquobahrie DA, Rice K, Williams OD, Williams MA, Gross MD, Lewis CE, Schwartz SM, Siscovick DS. 1L1B genetic variation and plasma C-reactive protein level among young adults: The CARDIA study. Atherosclerosis, 2008 May 18.
Thayagarajan B, Jacobs DR Jr, Apostol GG, Smith LJ, Jensen RL, Crapo RO, Barr RG, Lewis CE, Williams OD. Longitudinal association of body mass index with lung function: The CARDIA study. Respiratory Research. 2008 Apr 4; 9(1):31.
Sloan RP, Huang MH, McCreath H, Sidney S, Liu K, Williams OD, Seeman T. Cardiac autonomic control and the effects of age, race, and sex: the CARDIA study. Autonomic Neuroscience: Basic and Clinical. 2008 May 30; 139(1-2):78-85.
Salas M, Kiefe CI, Schreiner PJ, Kim Y, Juarez L, Person SD, Williams OD. Obesity modifies the association of race/ethnicity with medication adherence in the CARDIA study. Patient 2008; 1(1): 41-45.
Sternfeld B, Liu K, Quesenberry CP, Wang H, Jiang SF, Daviglus M, Fornage M, Lewis CE, Mahan J, Schreiner PJ, Schwartz SM, Sidney S, Williams OD, Siscovick DS. Changes over 14 years in androgenicity and body mass index in a bi-racial cohort of reproductive age women. Journal of Clinical Endocrinology and Metabolism 2008; as doi: 10.1210/jc.2007-2203.
Gilbert GH, Williams OD, Rindal DB, Philstrom DJ, Benjamin PL, Wallace MC; DPBRN Collaborative Group: The creation and development of the dental practice-based research network. Journal of the American Dental Association 2008 Jan; 139(1): 74-81.
Awards
Recipient of Dean's Excellence in Mentoring Award from University of Alabama at Birmingham, School of Medicine, 2008
Elected to present Richard D. Remington Methodology Lecture at the American Heart Association 40th Annual Conference on Cardiovascular Disease Epidemiology and Prevention, La Jolla CA, March 3, 2000
Certificate of Appreciation from the US National Heart, Lung, and Blood Institute and Poland’s Cardinal Wyszynski National Institute of Cardiology for work on the Poland-US Collaborative Study on Cardiovascular and Cardiopulmonary Epidemiology, 1998.
Nominated for American Heart Association International Program Committee, 1998.
Nominated for Teacher of the Year, UAB School of Public Health, 1998.
Outstanding Alumnus, Department of Biostatistics, School of Public Health, University of North Carolina, 1993
Outstanding Alumnus, Southeastern Louisiana University, May, 1991
The Wakeman Award for Research in the Neurosciences, in Recognition of Outstanding Professional Achievement, Awarded for Role on Monitoring Committee, National Acute Spinal Cord Injury Study II, 1990
Award Commemorating the 600th Anniversary of the Jagiellonian University and Faculty of Medicine for Contribution to Science and to the Polish-American Research Endeavors. Senate of the Nicolaus Copernicus Medical School, Krakow, Poland, 1988.
Certificate of Appreciation from James G. Martin, Governor of North Carolina, in Appreciation for Volunteer Services to the People of North Carolina, 1986
Award for Excellence, Statistics and Epidemiology Section, North Carolina Public Health Association, 1978
